Make Better Decisions with Evidence-based Comparisons in Atlas

Compare instruments in Atlas based on measure categories and evidence coverage to make informed decisions

Built on a strong foundation of ontological mapping and evidence coverage, the new Compare function represents a significant improvement to the analytical capabilities of the Atlas Platform.

Now, researchers can answer an important question even quicker: Which evidence-based measures do my selected technologies capture?

HumanFirst’s powerful measures ontologies make advanced comparisons possible by mapping vast amounts of digital biomarker and technology data to extensive underlying evidence. These ontologies enable teams to reliably navigate the universe of precision measurements available while ensuring research remains focused on what matters to their patient populations.

Additionally, researchers can view the most relevant evidence — in seconds. Underpinned by the V3 framework (co-authored by HumanFirst), Comparisons let teams stratify evidence by type — verification, analytical validation, and clinical validation. Proving evidentiary support for a technology is a necessary step when validating instruments for use in a clinical trial, and is why HumanFirst continues to invest in building the world’s most comprehensive evidence network for AI-powered digital biomarkers and eCOAs.

A clinical researcher prepares to analyze three sensor-based wearables in Atlas using an improved Compare function.

With today’s upgrade, users can compare 2+ technologies in order to

  • Determine similarities in measure categories and the source(s) of those claims
  • Contrast regulatory classification and evidence coverage across the V3 framework
  • Confirm population cohorts represented in the evidence for those instruments

Here’s how:

Confirm Measure Categories

Comparisons now expose measure categories for each instrument. Users can view and filter by the entity or source reporting that measure, whether derived directly from the evidence, from the instrument’s vendor, or from the FDA.

Using a “shared” filter, users can quickly isolate similarities in measures across the instruments being compared, which is particularly useful when targeting an instrument that can capture multiple measures to minimize operational complexity and cost as it relates to protocol design decisions.

Assess Evidence Coverage

The new evidence comparison quantifies coverage by total product evidence, total V3 evidence, and specific V3 type. FDA and CE Mark classifications offer an additional layer of regulatory validity.

Analyze Study Populations & Standard Attributes

Cohorts represented in the dataset for each instrument determine support for a given patient population, while granular technical specifications can be analyzed to determine fit for the trial.

Ready to take your research and analysis to new heights? Log in today to experience the new Comparisons.

Updates to Compare are the latest in our series of Atlas Platform enhancements that power collaborative research and decision-making. If you missed it, you can read more about the recent release of Atlas Projects in our blog.

Learn more about how HumanFirst is accelerating research using precision measures in their recent press release.

HumanFirst’s solutions have been used by leading academic medical institutions such as Harvard and Stanford, and by 24 out of 25 of the world’s largest pharmaceutical companies to unlock evidence-based precision measures that bring better treatments to market, faster.